Thám Tử Chuột Vĩ Đại

Frank Welker

Toby the Dog / Felicia the Cat (voice) (uncredited)

Vincent Price

Professor Ratigan (voice)

Tony Anselmo

Thug Guard (voice)

Basil Rathbone

Sherlock Holmes (voice)

Alan Young

Mr. Flaversham (voice)

Wayne Allwine

Thug Guard (voice)

Barrie Ingham

Basil of Baker Street / Bartholomew (voice)

Shani Wallis

Lady Mouse (voice)

Eve Brenner

The Mouse Queen (voice)

Walker Edmiston

Citizen / Thug Guard (voice)

Val Bettin

Dr. David Q. Dawson / Thug Guard (voice)

Candy Candido

Fidget (voice)

Laurie Main

Dr. Watson (archive sound)

Susanne Pollatschek

Olivia Flaversham (voice)

Diana Chesney

Mrs. Judson (voice)